What Makes Acanthamoeba Cyst?

Acanthamoeba exist in two forms: (i) an active trophozoite stage and (ii) a resistant double-walled cyst stage (Fig. 1). Encystment usually occurs on exposure of Acanthamoeba to harsh conditions such as change in pH, lack of nutrients, treatment with therapeutic agents etc.

What is an Acanthamoeba cyst?

Acanthamoeba is a genus of amoebae that are commonly recovered from soil, fresh water, and other habitats. Acanthamoeba has two evolutive forms, the metabolically active trophozoite and a dormant, stress-resistant cyst. Trophozoites are small, usually 15 to 25 μm in length and amoeboid in shape.

What causes Acanthamoeba?

This infection is caused by a microscopic, free-living ameba (single-celled living organism) called Acanthamoeba. Acanthamoeba causes Acanthamoeba keratitis when it infects the transparent outer covering of the eye called the cornea.