What's a Microsomal Fraction?
A Collection of Tiny Subcellular Particles, Invisible with the Light Microscope, That Are Produced During Differential Centrifugation of Eukaryotic Cells...
a collection of tiny subcellular particles, invisible with the light MICROSCOPE, that are produced during DIFFERENTIAL CENTRIFUGATION of eukaryotic cells. Under the ELECTRON MICROSCOPE, these microsomes can be seen to consist mainly of membranes and RIBOSOMES from the ENDOPLASMIC reticulum.
What is the meaning of microsomal?
1 : any of various minute cellular structures. 2 : a particle in a particulate fraction that is obtained by heavy centrifugation of broken cells and consists of various amounts of ribosomes, fragmented endoplasmic reticulum, and mitochondrial cristae.
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How do microsomes work?
Microsomes contain a group of proteins known as the cytochrome P450 proteins, which catalyse the transfer of a single oxygen atom to endogenous and exogenous substances destined for excretion and/or detoxification, such as steroids, phenobarbital, etc.