What's a Mononuclear Cells?

Mononuclear cells (MNCs) are a mixture of various different types of cells and contain most of the different stem cells within this component of the marrow, but principally contain a number of immature and mature cell types of different myeloid, lymphoid and erythroid lineages.

Where do mononuclear cells come from?

Peripheral blood mononuclear cells originate from hematopoietic stem cells (HSCs) that reside in the bone marrow. HSCs give rise to all blood cells of the immune system through a process called hematopoiesis.

What are the two types of mononuclear cells?

The two main types of leukocytes are granulocytes and mononuclear leukocytes (agranulocytes). ... Mononuclear leukocytes include lymphocytes, monocytes, macrophages, and dendritic cells. This group is involved in both innate and adaptive immune system function.