When Does Receptor Mediated Endocytosis Occur?

10.2.
Receptor-mediated endocytosis occurs with the binding of ligands to the specific receptors located in the luminal membrane of the BBB.

What is receptor-mediated endocytosis used for?

Receptor-mediated endocytosis is a form of endocytosis in which receptor proteins on the cell surface are used to capture a specific target molecule. The receptors, which are transmembrane proteins, cluster in regions of the plasma membrane known as coated pits.

What is required for receptor-mediated endocytosis?

Our biochemical and morphological data suggested that, although ATP is required for receptor-mediated endocytosis, in ATP-depleted cells ligands can become efficiently sequestered into deeply invaginated pits that are inaccessible to large probes such as antibodies, but remain accessible to small molecules such as GSH.

Chloe Bennett

Chloe Bennett

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