When to Start Thyroxine in Pregnancy?
Levothyroxine Requirements Increase as Early as the Fifth Week of Gestation. Given the Importance of Maternal Euthyroidism for Normal Fetal Cognitive...
Levothyroxine requirements increase as early as the fifth week of gestation. Given the importance of maternal euthyroidism for normal fetal cognitive development, we propose that women with hypothyroidism increase their levothyroxine dose by approximately 30 percent as soon as pregnancy is confirmed.
When should thyroid medication be taken during pregnancy?
Most providers treat pregnant women with an overactive thyroid with antithyroid medicines called propylthiouracil in the first trimester and methimazole in the second and third trimesters. The timing of these medicines is important. Propylthiouracil after the first trimester can lead to liver problems.
What should be the TSH level during pregnancy?
The Endocrine Society recommends that TSH levels be maintained between 0.2-<2.5 mU/L in the first trimester of pregnancy and between 0.3-3 mU/L in the remaining trimesters. The aim of this study was to examine the relationship between TSH levels in early pregnancy and the risk of adverse pregnancy outcomes.
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