Where Can Mononuclear Phagocytes Be Found?

Mononuclear phagocytic cells are derived from precursor cells in the bone marrow. These precursors develop into monocytes and dendritic cells, phagocytic cells that are released into the bloodstream.

Which cells belong to mononuclear phagocyte system?

The mononuclear phagocyte system (MPS) has been defined as a family of cells comprising bone marrow progenitors, blood monocytes and tissue macrophages. Macrophages are a major cell population in most of the tissues in the body, and their numbers increase further in inflammation, wounding and malignancy.

What is the function of mononuclear phagocytes?

Mononuclear phagocytes are also produced during adult hematopoiesis; these cells are then recruited to sites throughout the body, where they function in tissue repair and remodeling, resolution of inflammation, maintenance of homeostasis, and disease progression.