Where Does Aldosterone Exert Its Effects?

Aldosterone, a steroid hormone with mineralocorticoid activity, is mainly recognized for its action on sodium reabsorption in the distal nephron of the kidney, which is mediated by the epithelial sodium channel (ENaC).

Where does aldosterone exert its effects quizlet?

Where in the kidney does aldosterone exert its action? cortex. powerful vasoconstrictor to increase blood pressure. It stimulates thirst and ADH release by the posterior pituitary gland (for water retention).

Where does aldosterone exert its effect in nephron?

Aldosterone acts on the distal tubule to retain sodium and excrete potassium by inhibition of sodium-potassium exchange (see Fig. 5-4). Water is retained with sodium. In heart failure, plasma aldosterone rises up to 20 times normal in response to increased angiotensin II coupled with decreased hepatic clearance.