Where Is Mannose Binding Lectin Found?
It Is Produced in the Liver as a Response to Infection, and Is Part of Many Other Factors Termed Acute Phase Proteins. Expression and Function in Other Organs...
It is produced in the liver as a response to infection, and is part of many other factors termed acute phase proteins. Expression and function in other organs were also suggested.
What is normal mannose binding lectin?
Normal serum levels of MBL range from 800 to 1000 ng/ml in healthy Caucasians, however, wide variations can occur due to point mutations in codons 52, 54 and 57 of exon 1 and/or in the promotor region of the MBL gene [3].
What does mannose binding lectin Recognise?
MBL recognizes specific carbohydrates such as d-mannose, l-fucose and N-acetylglucosamine that are represented on the surface of a wide variety of infectious agents (Figure 1b) [1]. Pathogens targeted by MBL include certain Gram-positive and Gram-negative bacteria, yeast, parasites and viruses [9].
Elena Rostova holds a Master's degree in Public Health Journalism. She covers groundbreaking medical research, holistic wellness trends, mental health awareness, and nutritional science.
