Where Is Nifedipine Absorbed?

Nifedipine is almost completely absorbed from the gastrointestinal tract as shown by plasma levels after sublingual, oral, and rectal administration. Because of presystemic metabolism, the bioavailability is about 56% to 77%.

Where is nifedipine metabolism?

Distribution: About 92% to 98% of circulating nifedipine is bound to plasma proteins. Metabolism: Metabolized in the liver. Excretion: Excreted in urine and feces as inactive metabolites. Elimination half-life is 2 to 5 hours.

How does nifedipine work in the body?

Nifedipine is a type of medicine called a calcium channel blocker. If you have high blood pressure, it works by blocking calcium going into muscles in the heart and blood vessels. Muscles need calcium to contract, so when you block the calcium, it makes the muscle cells relax.

Alexander Ross

Alexander Ross

Gaming, Esports & Interactive Media Writer

Alexander Ross has covered the video game industry for a decade, writing deep dives on game design, esports tournaments, VR developments, and gaming culture.