Where Is Thyroglobulin Synthesis?

Thyroglobulin (Tg) is a vertebrate secretory protein synthesized in the thyrocyte endoplasmic reticulum (ER), where it acquires N-linked glycosylation and conformational maturation (including formation of many disulfide bonds), leading to homodimerization.

What is thyroglobulin and where is it produced?

Thyroglobulin is a protein made by cells in the thyroid. The thyroid is a small, butterfly-shaped gland located near the throat.

Where is T3 synthesized?

thyroxine (T4) and triiodothyronine (T3) are produced from thyroid follicular cells within the thyroid gland, a process regulated by the thyroid-stimulating hormone secreted by the anterior pituitary gland.