Which Blood Thinners Have Reversal Agents?

Sarah Jenkins
Sarah Jenkins
• • 6 min read

Pradaxa Pradaxa the 150 Mg Capsule for Oral Administration Contains 172.95 Mg Dabigatran Etexilate Mesylate, Which Is Equivalent to 150 Mg of Dabigatran...

Which Blood Thinners Have Reversal Agents?

Pradaxa

Pradaxa
The 150 mg capsule for oral administration contains 172.95 mg dabigatran etexilate mesylate, which is equivalent to 150 mg of dabigatran etexilate, and the following inactive ingredients: acacia, dimethicone, hypromellose, hydroxypropyl cellulose, talc, and tartaric acid.
and warfarin now have reversal agents, and there is much interest in developing such agents for the other drugs in this class.

Which anticoagulant has a reversal agent?

Idarucizumab and andexanet alfa, which reverse the anticoagulant effects of dabigatran and FXa inhibitors, respectively, are DOAC reversal agents available in the US. Other reversal agents (e.g. ciraparantag for heparins, DOACs) are in development.

Must Read

What blood thinners can be reversed?

The FDA approved andexanet alfa (AndexXa) on May 3, 2018. It's the first and only antidote to reverse bleeding in people taking apixaban (Eliquis), rivaroxaban (Xarelto), or edoxaban (Savaysa). Another newer blood thinner — dabigatran (Pradaxa) — already has an approved antidote called idarucizumab (Praxbind).

Sarah Jenkins

Sarah Jenkins

Senior Technology Editor & AI Specialist
Twitter Linkedin Github

Sarah Jenkins is a veteran tech journalist with over 12 years of experience covering artificial intelligence, mobile innovations, and digital ethics. Her insights have appeared in leading technology publications worldwide.