Which Drugs Affect Ptt Lab Values?
Which Factors May Interfere with an Activated Partial Thromboplastin Time (Aptt) Test? Drugs That May Prolong the Test Values, Including Antihistamines...
Which factors may interfere with an activated partial thromboplastin time (aPTT) test?
- Drugs that may prolong the test values, including antihistamines, ascorbic acid, chlorpromazine, heparin, and salicylates.
- Incorrect blood-to-citrate ratio.
- Hematocrit that is highly increased or decreased.
What can cause elevated PTT?
Diagnoses associated with an elevated PTT include:
- Hemophilia A (Factor VIII deficiency) Factor VIII deficiency characterizes Hemophilia A, also known as classical hemophilia. ...
- Hemophilia B (Factor IX deficiency) ...
- Vitamin K Deficiency. ...
- Liver Disease. ...
- Von Willebrand Disease (VWD) ...
- Disseminated Intravascular Coagulation (DIC)
What can affect PTT levels?
Several factors can affect results of a PTT and the interpretation of test results: People with high hematocrit levels may have falsely prolonged PTTs. Heparin contamination – this is the most common problem, especially when blood is collected from intravenous lines that are being kept “open” with heparin flushes.
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