Which Leukoplakia Has Highest Malignant Potential?

Oral leukoplakia is the most common potentially malignant lesion of the oral cavity, it is estimated that the overall prevalence is 1.72-2.60% (1).

Which type of leukoplakia has highest malignant transformation?

Malignant transformation rates of oral leukoplakia range from 0.13 to 17.5%, while the rates of five-year cumulative malignant transformation range from 1.2 to 14.5%.

Which leukoplakia is cancerous?

Most leukoplakia patches are noncancerous (benign), though some show early signs of cancer. Cancers on the bottom of the mouth can occur next to areas of leukoplakia. And white areas mixed in with red areas (speckled leukoplakia) may indicate the potential for cancer.