Which Nephron Produces More Concentrated Urine?

Although both cortical and juxtamedullary nephrons regulate the concentrations of solutes and water in the blood, countercurrent multiplication in the loops of Henle of juxtamedullary nephrons is largely responsible for developing the osmotic gradients that are needed to concentrate urine.

What nephron produces concentrated urine?

The renal medulla produces concentrated urine through the generation of an osmotic gradient extending from the cortico-medullary boundary to the inner medullary tip.

Where is the urine most concentrated in the nephron?

Maximum concentration occurs at the bottom of the loop. The ascending limb of the nephron loop is impermeable to water, but Na ⁺ and Cl ^– are pumped out into the surrounding fluids by active transport.