Which One Is Nephrotoxin?

A nephrotoxin is a toxic agent or substance that inhibits, damages or destroys the cells and/or tissues of the kidneys. This is an example of a cytotoxin. The adjective form is nephrotoxic. Inflammation of the kidneys is called nephritis.

Which drugs are nephrotoxic?

The nephrotoxic effects of cyclosporine, aminoglycoside antibiotics, cisplatin, amphotericin B, beta-lactam antibiotics and indomethacin are reviewed. These drugs were chosen because they are among the most frequent causes of renal injury in children. In addition, their nephrotoxicity is caused by different mechanisms.

What is a Nephrotoxin?

Nephrotoxins are substances displaying nephrotoxicity. Different mechanisms lead to nephrotoxicity, including renal tubular toxicity, inflammation, glomerular damage, crystal nephropathy, and thrombotic microangiopathy.

Sarah Jenkins

Sarah Jenkins

Senior Technology Editor & AI Specialist

Sarah Jenkins is a veteran tech journalist with over 12 years of experience covering artificial intelligence, mobile innovations, and digital ethics. Her insights have appeared in leading technology publications worldwide.