Which Pfizer Shot Is Worse?

Why are Pfizer and Moderna side effects worse after the second shot? The second dose of the Pfizer and Moderna vaccines is likely to cause more noticeable side effects. In both the Pfizer and Moderna vaccine clinical trials, more participants had symptoms like headache, fever, and body aches after the second dose.

What is the difference between Pfizer and Moderna vaccine?

Moderna's shot contains 100 micrograms of vaccine, more than three times the 30 micrograms in the Pfizer shot. And Pfizer's two doses are given three weeks apart, while Moderna's two-shot regimen is administered with a four-week gap.

Are the Pfizer and Moderna COVID-19 vaccines interchangeable?

COVID-19 vaccines are not interchangeable. If you received a Pfizer-BioNTech or Moderna COVID-19 vaccine, you should get the same product for your second shot. You should get your second shot even if you have side effects after the first shot, unless a vaccination provider or your doctor tells you not to get it.