Who Classification Intraepithelial Neoplasia?

Cervical intraepithelial neoplasia may be classified according to how much epithelial tissue is affected: Low-grade neoplasia (CIN 1) refers to dysplasia that involves about one-third of the thickness of the epithelium. CIN 2 refers to abnormal changes in about one-third to two-thirds of the epithelial layer.

How is CIN determined?

CIN is usually discovered by a screening test, the Pap smear. The purpose of this test is to detect potentially precancerous changes through random sampling of the transformation zone. Pap smear results may be reported using the Bethesda system (see above).

What is the difference between CIN 1/2 and 3?

CIN 2 – there's a moderate chance the cells will become cancerous and treatment to remove them is usually recommended. CIN 3 – there's a high chance the cells will become cancerous and treatment to remove them is recommended.