Who Do Diuretics Cause Hyperlipidemia?

Hyperlipidemia is prevalent in hypertension, but the cause of this association is unknown. Treatment of hypertension with thiazide diuretics accentuates the hyperlipidemia, perhaps by causing potassium or sodium depletion.

How do diuretics affect cholesterol?

It's from a class of medications called diuretics, more commonly known as water pills. High doses — 50 milligrams or more — of some diuretics, including hydrochlorothiazide, can temporarily increase your low-density lipoprotein (LDL) cholesterol — the "bad" cholesterol — and triglycerides.

How does thiazide increase LDL?

Cardiovascular Drugs Have Variable Effects

Thiazide and loop diuretics increase serum total cholesterol and low density lipoprotein (LDL)-cholesterol levels by up to 5 to 10%. Although high density lipoprotein (HDL)-cholesterol levels are not affected, triglyceride levels are elevated by 5 to 15%.