Who's Vadas Real Dad?

When one or two people talk about a relationship her mother had with another man before Harry, Vada wonders is he is her true biological father, and the man she ponders is her real father is Jeffrey Pommeroy (John David Souther).

Are Vada and Nick related?

Nick is the son of Uncle Phil's girlfriend Rose (Ebersole), and he is asked to show Vada around the city. While annoyed at first about sacrificing his own spring break, he helps Vada with the difficult search of learning more about her mother. Their relationship, which starts out reluctantly, gradually grows stronger.

What is wrong with Vada in My Girl?

Vada, the precocious 11-year-old heroine of "My Girl," has a lot to worry about. There's the chicken bone lodged in her throat, the abnormal development of her breasts, and the disturbing symptoms of prostate cancer. ... The doctor, of course, can find nothing wrong, but Vada is unconvinced.