Why Are Osteoclasts Multinucleated?
Osteoclasts Are Multinucleated Cells Derived from Hemopoietic Progenitors of the Monocyte-Macrophage Lineage. They Differentiate Upon Exposure to Macrophage...
Osteoclasts are multinucleated cells derived from hemopoietic progenitors of the monocyte-macrophage lineage. They differentiate upon exposure to macrophage colony stimulating factor (M-CSF) and receptor activator of NF-κB ligand (RANKL), which are presented by osteoblasts and
Are osteoclasts multinucleated?
Osteoclasts are multinucleated cells that derive from hematopoietic progenitors in the bone marrow which also give rise to monocytes in peripheral blood, and to the various types of tissue macrophages. Osteoclasts are formed by the fusion of precursor cells.
What is the function of multinucleated osteoclast cells?
Osteoclast, large multinucleated cell responsible for the dissolution and absorption of bone. Bone is a dynamic tissue that is continuously being broken down and restructured in response to such influences as structural stress and the body's requirement for calcium.
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