Why Corrected Reticulocyte Count?

The reticulocyte production index (RPI), also called a corrected reticulocyte count (CRC), is a calculated value used in the diagnosis of anemia. This calculation is necessary because the raw reticulocyte count is misleading in anemic patients.

When should reticulocyte count be corrected?

Thus, in the setting of acute blood loss, the reticulocyte count is most helpful when the bleeding and subsequent anemia have been present for more than a few days. If the corrected reticulocyte count is greater than 2%, then the bone marrow is producing RBCs at an accelerated pace (Fig.

What does high corrected reticulocyte count mean?

Why It Is Done

Check how well bone marrow is working to make red blood cells. Check to see if treatment for anemia is working. For example, a higher reticulocyte count means that iron replacement treatment or other treatment to reverse the anemia is working.