Why Dic Occurs in Abruptio Placentae?

DIC may occur in placental abruption involving liberation of tissue thromboplastin or possible intrauterine consumption of fibrinogen and coagulation factors during the formation of retro- placental clot. This leads to activation of the extrinsic coagulation mechanism.

How does placental abruption cause DIC?

In cases of DIC due to placental abruption, the tissue factor thromboplastin flows from a retroplacental hematoma into the maternal circulation, resulting in consumption coagulopathy via the activation of an extrinsic coagulation cascade [4].

Why does IUFD cause DIC?

Several diseases are known to be associated with DIC, some of which may also occur during pregnancy or the puerperium. One of the potential risk factors that have been considered as a potential trigger for DIC is the retention of a highly macerated fetus after intrauterine fetal death (IUFD).