Why Do Inr Levels Go up and Down

Foods with high levels of vitamin K include kale, broccoli, and Brussels sprouts. Other changes to your nutrition, such as starting a new diet or taking new supplements, can also cause your INR level to fluctuate. Talk to your doctor before starting any new diet/nutrition regimens.

Is it normal for INR to fluctuate?

There are many reasons for variance in INR’s in patients on warfarin. Even a patient who has been stabilized on warfarin for some time may experience unexpected fluctuations. These fluctuations may be driven by both pharmacokinetic (eg drug interactions) and/or pharmacodynamic (eg vitamin K intake) factors.

What can increase or decrease INR?

• If you eat more vitamin K, it can lower your INR.
• If you eat less vitamin K, it can raise your INR.