Why Does Scleroderma Cause Gerd?

When the muscles of the gastrointestinal tract are involved, the esophagus may be hit the hardest. “Patients with scleroderma can have very severe GERD due to involvement of the smooth muscle in the [lower] two-thirds of the esophagus, including the lower esophageal sphincter,” says gastroenterologist Lauren B.

How does scleroderma cause reflux?

In systemic scleroderma, the gate does not close properly and the result is a backwash of acid and a burning sensation (heartburn) as food and acid return into the esophagus. The acid may also injure the lining of the lower portion of the esophagus, causing scarring and a narrowing (stricture) of the tube.

What does scleroderma do to the esophagus?

Patients with scleroderma of the esophagus typically lack this peristaltic contraction, which is called aperistalsis. When this occurs, foods, particularly solids, hang up in the esophagus and produce dysphagia (the sensation that food is stuck in the chest).