Why Drysol at Night?

Drysol deodorant/antiperspirant penetrates sweat glands and blocks them from producing sweat. You apply it overnight because you sweat less while sleeping. You're supposed to notice an improvement after several nightly treatments.

Why does Drysol need to be applied at night?

Drysol is applied at bedtime to completely dry skin and washed off in the morning shower. ... The medication is less effective on the thick skin of the palms and soles.

Can you put Drysol on in the morning?

Another of the things to consider when learning how to use Drysol, is that it needs to be thoroughly washed off in the morning prior to applying deodorant. Also, if using the milder solution for face, hands, and the soles of feet, those areas will need to be washed as well before starting the day.