Why Is D5W Contraindicated When Transfusing Blood?

D5W and dextrose solutions will cause clumping and hemolysis • Solutions containing calcium may cause clotting due to calcium content. IVIG is compatible with D5W.

Can you transfuse blood with D5W?

Intravenous immunoglobulin (IVIG) is only compatible with D5W. All blood products taken from the blood bank must be hung within 30 minutes and administered (infused) within 4 hours due to the risk of bacterial proliferation in the blood component at room temperature.

What happens when blood is administered with dextrose?

Lactated Ringer's solution and 5 per cent dextrose in 0.225 per cent saline should not be administered concurrently with blood. Lactated Ringer's solution may also be harmful when used to start transfusions as it rapidly produces clots when mixed with CPD blood.