Why Is Gentamicin Given Intravenously?

Gentamicin injection is used to treat certain serious infections that are caused by bacteria such as meningitis (infection of the membranes that surround the brain and spinal cord) and infections of the blood, abdomen (stomach area), lungs, skin, bones, joints, and urinary tract.

Why is gentamicin not given orally?

Aminoglycosides such as gentamicin cannot be administered orally for treatment of systemic infection because they are not absorbed from the intact gastrointestinal tract [294]. Analysis of peak and trough concentrations reveal significant interpatient variability within and between studies.

Can gentamicin be given intravenously?

Gentamicin is indicated in the treatment of the following infections when caused by susceptible organisms. Burns and serious skin lesions. Gentamicin is normally given by the intramuscular route, but can be given intravenously when intramuscular administration is not feasible.