Why Is Sparteine Used?
(−)-Sparteine Is the Best Known of the Naturally Occurring Lupin Alkaloids, Isolated from Leguminous Plants. This Natural Product Is a Cardiovascular Agent and...
(−)-Sparteine is the best known of the naturally occurring lupin alkaloids, isolated from leguminous plants. This natural product is a cardiovascular agent and it is also important due to its widespread use as a chiral ligand in asymmetric synthesis.
What is sparteine used for?
A quinolizidine alkaloid isolated from several FABACEAE including LUPINUS; SPARTIUM; and CYTISUS. It has been used as an oxytocic and an anti-arrhythmia agent. It has also been of interest as an indicator of CYP2D6 genotype.
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Which drug contain sparteine?
Sparteine is a class 1a antiarrhythmic agent; a sodium channel blocker. It is an alkaloid and can be extracted from scotch broom. It is the predominant alkaloid in Lupinus mutabilis, and is thought to chelate the bivalent cations calcium and magnesium.
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