Why Is Urine Sodium Elevated in Siadh

In SIADH, the excess of ADH results in water retention, but not solute retention. As a result, concentrated urine which is relatively high in sodium is produced, despite low serum sodium.

Is urine sodium high in SIADH?

In SIADH, the urine sodium concentration is usually above 40 mEq/L, the serum potassium concentration is normal, there is no acid-base disturbance, and the serum uric acid concentration is frequently low [1]. (See “Diagnostic evaluation of adults with hyponatremia”.)

How does ADH affect urine sodium?

Vasopressin (also called antidiuretic hormone) helps regulate the amount of water in the body by controlling how much water is excreted by the kidneys. Vasopressin decreases water excretion by the kidneys. As a result, more water is retained in the body, which dilutes the level of sodium in the body.

Alexander Ross

Alexander Ross

Gaming, Esports & Interactive Media Writer

Alexander Ross has covered the video game industry for a decade, writing deep dives on game design, esports tournaments, VR developments, and gaming culture.

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