Why Sgpt Increase in Dengue?

Liver enzyme elevations are common in dengue. Usually the SGOT levels are more than SGPT levels probably due to skeletal muscle injury. Occasionally jaundice is also seen [2].

Does SGPT increased in dengue?

Liver involvement is one of the common features in dengue fever. Various studies have shown that in all those patients who develop complications like dengue hemorrhagic fever, dengue shock syndrome the levels of SGOT and SGPT were significantly raised.

Why is liver affected in dengue?

Dengue causes liver damage through multiple mechanisms: direct viral effects on hepatocytes and Kupffer cells, immunologic hyperactivity via a T cell-mediated cytokine storm, and circulatory failure that leads to decreased hepatic perfusion.