Why Use Constitutive Promoter?
Constitutive Promoters Are Used Routinely to Drive Ectopic Gene Expression. .. . We Found That These Promoters Vary Considerably from One Another in Their...
Constitutive promoters are used routinely to drive ectopic gene expression. ... We found that these promoters vary considerably from one another in their strength. Most promoters have fairly consistent strengths across different cell types, but the CMV promoter can vary considerably from cell type to cell type.
Why is it advantageous to have constitutive promoters?
Strong constitutive promoters can deliver a high-level expression of transgenes to almost all tissues and development stages in plants, which is particularly useful for the expression of herbicide tolerance, insect resistance and selectable marker genes [3].
What is a constitutive promoter?
Constitutive promoters are defined as promoters active in vivo in all circumstances, and, on the other hand, inducible promoters are switched ON and OFF by transcription factors depending on the in vivo conditions (Shimada et al., 2014).