Will Benadryl Help Atopic Dermatitis?

Oral antihistamines, like Benadryl or Claritin, can also be added to help with itching. Atopic dermatitis is a condition that is difficult for many patients to fully control. Recently, two new treatments have been approved for atopic dermatitis and have shown significant improvement in control of this condition.

What is the best antihistamine for atopic dermatitis?

Take an oral allergy or anti-itch medication.

Options include nonprescription allergy medicines (antihistamines) — such as cetirizine (Zyrtec) or fexofenadine (Allegra). Also, diphenhydramine (Benadryl, others) may be helpful if itching is severe. But it causes drowsiness, so it's better for bedtime.

Can antihistamines help atopic dermatitis?

Traditionally, antihistamines are being used to treat itching which is the crucial sign of atopic dermatitis with a major impact on health-related quality of life. Besides the antihistamine and anti-inflammatory effects of antihistamines, the sedative action of the treatment is rather useful.