Will Benadryl Help My Eczema?

Although there are many treatments for eczema, you might wonder whether over-the-counter (OTC) options such as Benadryl can help. Although Benadryl is helpful for allergies and itchy skin from hives or bug bites, it is not recommended for eczema and is ineffective for treating it.

Does Benadryl help with eczema flare ups?

Antihistamines: These drugs won't stop a flare, but they may be able to relieve itching. Diphenhydramine ( Benadryl), which you can buy at the store, is a good choice. So are hydroxyzine (Atarax) and cyproheptadine (Periactin), which your doctor can prescribe. Take them at night, as all of these will make you sleepy.

Can antihistamines help with eczema?

Antihistamines are a type of medicine that block the effects of a substance in the blood called histamine. They can help relieve the itching associated with atopic eczema.