Will Sedation Lower Blood Pressure?

Benzodiazepines, such as midazolam and diazepam, have a mild vasodilator effect and usually produce a slight fall in arterial blood pressure, even in normal sedative doses. The combination use of a benzodiazepine and an opioid can profoundly drop blood pressure.

Can you be sedated with high blood pressure?

Do not use local anesthetics with vasoconstrictors in patients with uncontrolled or poorly controlled hypertension. This is defined as any patient with a systolic blood pressure greater than or equal to 180 mmHg and/or a diastolic blood pressure greater than or equal to 100 mmHg.

How do sedatives affect blood pressure?

profile for sedation. It causes a decrease in cerebral metabolism, blood flow, and intracranial pressure. It has been shown to cause profound hypotension when given as a bolus; this effect is most likely due to direct myocardial depression and a decrease in systemic vascular resistance.