At Complementary Base Pairing?

Chargaff's rule, also known as the complementary base pairing rule, states that DNA base pairs are always adenine with thymine (A-T) and cytosine with guanine (C-G). A purine always pairs with a pyrimidine and vice versa. However, A doesn't pair with C, despite that being a purine and a pyrimidine.

What is the complementary base pairing?

Explanation: The four nitrogenous bases of DNA are thymine, adenine, guanine, and cytosine. Guanine and cytosine are bound together by three hydrogen bonds; whereas, adenine and thymine are bound together by two hydrogen bonds. This is known as complementary base pairing.

Are A and T complementary?

There are chemical cross-links between the two strands in DNA, formed by pairs of bases. They always pair up in a particular way, called complementary base pairing: thymine pairs with adenine (T–A)