Why Was Fen-Phen Banned

In 1997, the FDA ordered Wyeth to remove fenfluramine (Pondimin) and a related drug, dexfenfluramine (Redux) from the market, after a study showed they caused damage to heart valves. That effectively put an end to the fen-phen craze.

Can you still get Phen Fen?

Fen-phen is no longer widely available.

What does phen phen do to your heart?

Fen and two migraine drugs, ergotamine and methysergide, which also are known to cause heart valve damage, were found to activate the serotonin receptor known as 5-HT2B located on heart’s valves (both the mitral and aortic).

Sarah Jenkins

Sarah Jenkins

Senior Technology Editor & AI Specialist

Sarah Jenkins is a veteran tech journalist with over 12 years of experience covering artificial intelligence, mobile innovations, and digital ethics. Her insights have appeared in leading technology publications worldwide.

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